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KMID : 1101720150190030247
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Physical Activity and Nutrition
2015 Volume.19 No. 3 p.247 ~ p.254
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Effects of skim milk powder intake and treadmill training exercise on renal, bone and metabolic parameters in aged obese rats
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Oh Tae-Woong
Igawa Shoji
Naka Tatsuki
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Abstract
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Purpose :we aim to examine whether adding exercise has impact on obesity prevention and bone metabolism in senior rats, to which dietary obesity was induced through skim milk intake.
Methods :We used 47, 14-week old Sprague -Dawley (SD) female rats (CLEA Japan, Inc.). The Rats were separated into four random groups: 1) a Non-Ex group with a normal diet (n = 12), 2) an Ex group with a normal diet (n = 12), 3) a Non-Ex group with a skim milk diet (n = 11), and 4) an Ex group with a skim milk diet (n = 12). As the exercise for each Ex group, rats ran on a treadmill starting at 27-week old (TREADMILL CONTROL LE8710 and TREADMILL CONTROL LE8700, Harvard Bioscience). Training protocol stipulated a frequency of five times a week for 12 weeks.
Results :The leptin concentration differed with dietary content: compared to the Ex group with a skim milk diet, Non-Ex and Ex groups with a normal diet showed significantly higher values (p < 0.05). The Ex group had significantly lower values in both the normal diet and skim milk diet groups with or without exercise (p < 0.05). Compared to the Non-Ex group with a normal diet, BS/BV (mm2/mm3), BV/TV (%), Tb.Th (μm), TBPf (/mm) and Tb.N (/mm) had significantly lower in the Ex group, the Ex and Non-Ex groups with a whey protein diet, and the Ex group with a skim milk protein diet (p < 0.05).
Conclusion :These findings suggest that senior female rats fed SMP would have higher bone structural and strength parameters than rats fed a normal diet.
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KEYWORD
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Skim milk, exercise, bone, metabolic parameters, aged, rat
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